GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs703842 | 1 | rs10877019 | chr12:58172929 | FAM119B | chr12:58166383-58176323:+ | -0.27 | -4.19 | 3.47E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877019 | chr12:58172929 | TSFM | chr12:58176536-58191367:+ | 0.37 | 6.62 | 1.21E-10 | Multiple sclerosis |
| BLCA | cis | rs56322409 | 1 | rs10882644 | chr10:97388579 | ENTPD1 | chr10:97471536-97637022:+ | 0.19 | 4.92 | 1.32E-6 | Blood metabolite levels |
| BLCA | cis | rs12045807 | 1 | rs10888396 | chr1:150777514 | HORMAD1 | chr1:150670542-150693352:- | 0.4 | 4.17 | 3.72E-5 | Congenital left-sided heart lesions |
| BLCA | cis | rs2275426 | 1 | rs10890352 | chr1:46283628 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -6.99 | 1.19E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs10890354 | chr1:46305347 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs10890361 | chr1:46346234 | CCDC163P | chr1:45960581-45965646:- | -0.35 | -6.6 | 1.37E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs10890363 | chr1:46356148 | CCDC163P | chr1:45960581-45965646:- | 0.37 | 7.01 | 1.09E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs10890383 | chr1:46588503 | CCDC163P | chr1:45960581-45965646:- | -0.32 | -5.88 | 8.8E-9 | Body mass index |
| BLCA | cis | rs3829251 | 1 | rs10898211 | chr11:71210677 | KRTAP5-10 | chr11:71276609-71277666:+ | 0.2 | 3.87 | 0.000128 | Vitamin D levels |
| BLCA | cis | rs3829251 | 1 | rs10898234 | chr11:71236684 | KRTAP5-10 | chr11:71276609-71277666:+ | 0.2 | 3.83 | 0.000151 | Vitamin D levels |
| BLCA | cis | rs6598955 | 1 | rs10902728 | chr1:26598281 | ZNF593 | chr1:26496388-26497362:+ | 0.21 | 4.35 | 1.77E-5 | Obesity-related traits |
| BLCA | cis | rs6684514 | 1 | rs10908498 | chr1:156278175 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.92 | 0.000107 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs6684514 | 1 | rs10908499 | chr1:156279176 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.92 | 0.000107 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs6684514 | 1 | rs10908500 | chr1:156280671 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 4.05 | 6.15E-5 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |